Barcelona out of Champions League after Inter Milan beat Viktoria Plzen

Barca will have to settle for a Europa League place.

Barcelona were eliminated from the Champions League after Inter Milan stormed to a dominant 4-0 win over Viktoria Plzen at San Siro.

Edin Dzeko scored twice as Inter booked their place in the last 16, joining Bayern Munich in qualifying from Group C, with five-time European champions Barca having to settle for a Europa League place.

Henrikh Mkhitaryan opened the scoring for the home side in the 35th minute from an Alessandro Bastoni cross, before Dzeko had his first of the night with a tap-in at the far post, converting from a well-timed ball from Federico Dimarco.

Italy Soccer Champions League — Edin Dzeko scored twice for Inter Milan (Luca Bruno/AP)

Barcelona went on to lose 3-0 at home to Group C winners Bayern Munich.

The Bundesliga outfit got off to a good start when Sadio Mane opened the scoring in the 10th minute.

Eric Choupo-Moting added a second before half-time, with Benjamin Pavard completing the scoring in the fifth minute of stoppage time.

Barcelona's tournament exit was already confirmed before their 3-0 defeat — Barcelona’s exit was already confirmed before their 3-0 defeat (Joan Monfort/AP)

Giovanni Simeone scored twice in the first 16 minutes before Leo Ostigard sealed victory with an 80th-minute header.

Liverpool qualified for the last 16 after beating Ajax 3-0.

Darwin Nunez found the net as Liverpool secured their place in the last 16 with a 3-0 win at Ajax (Zac Goodwin/PA)

In Group D, Harry Kane’s last-gasp winner was ruled out by VAR to leave Tottenham’s hopes of reaching the last 16 in the balance after a 1-1 draw against Sporting Lisbon.

Spurs thought they had won the match when Kane found the back of the net but after a long VAR review, it was ruled out for offside.

Former Spurs youth player Marcus Edwards put the visitors ahead, but it was cancelled out by Rodrigo Bentacur 10 minutes from time.

Diogo Costa saved two penalties as Porto beat Club Bruges 4-0.

Also in Group B, Atletico Madrid missed a last-gasp penalty as they crashed out following a 2-2 draw with Bayer Leverkusen.

Lukas Hradecky saved from Yannick Carrasco from 12 yards, the follow-up was headed onto the crossbar and a third chance deflected over to leave both sides fighting for a Europa League spot.